Effective Utilization of Trending in the Laboratory

Tiffany Coleman, Sequence QCS
Daniel Santarsiero, Sequence QCS

A review of successful and unsuccessful trending mechanisms in LIMS and facility monitoring tools. Including a discussion of utilities controls, sample storage controls, instrumentation maintenance controls, and safety monitoring controls. A focus on the difference between available control mechanisms and lessons learned during upgrades from one type of control to another. Examples of controls - spreadsheet standard drift monitoring for analytical instruments, TOC monitoring for standard preparation, CO2 monitoring for microbiological incubation, temperature cycle monitoring for cold storage on pen chart recorders, digital chart recorders, and using BAS monitoring systems.

The goal is to foster discussion on utilizing trending to identify weak links in established facilities to realize either materials or energy reductions to boost sustainability. While identifying other issues beyond sustainability that can be improved by trend monitoring.

Learning Objectives

  • Participants will be able to identify trending tools that already exist within their laboratories.
  • Participants will be able to analyze the risk that a change to the identified trending tools would have on their laboratory.
  • Participants will evaluate the difference between digital trending historians and analog trending historians.
  • Participants will employ established trending techniques utilizing pre-existing tools to minimize material and energy usage within the laboratory.


Tiffany has been working in the industry since 2001. Starting with undergraduate research in neurobiology and continuing onto organic synthesis and small molecule pharmaceutical products, she has a great love of data and scientific theory. A graduate of UMKC - she has long been an advocate for industry established quality practices and works directly with professionals as a project manager to define a higher standard of success through risk analysis and industry best practices.


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